Made for Pharma and BioTech companies

Are you looking for a reliable partner?

Our genomics solutions support you along your theɾapeutics development chain of small and large molecules

Eurofins pharma solutions

Solutions you need

Get best in class pharmacogenomics service and support for your project. Our experts would love to discuss the details of your project with you.
Eurofins pharma technologies

Essential technologies

We offer the latest technology and tools in many business areas. We support you with our pharmacogenomics solutions in every stage of your process.
Eurofins pharma accreditations

Accreditations you expect

We know that complying with your requirements is a must, so all our labs are certified. Quality and reliability means everything to us.
Eurofins pharma solutions

Solutions you need

Get best in class pharmacogenomics service and support for your project. Our experts would love to discuss the details of your project with you.
Eurofins pharma technologies

Essential technologies

We offer the latest technology and tools in many business areas. We support you with our pharmacogenomics solutions in every stage of your process.
Eurofins pharma accreditations

Accreditations you expect

We know that complying with your requirements is a must, so all our labs are certified. Quality and reliability means everything to us.
Does this sound familiar to you?

Your pharma challenges

  • Complex project set-up
  • Many different stakeholders
  • High requirements for accreditations and certificates (ISO)
  • Too many different service providers that only cover one aspect of the project
  • Often changing contact persons

We have 30 years of expertise, a wide network of laboratories, and a pharmacogenomics product portfolio that supports your entire value chain.

Our GENOMICS Solutions for PHARMA / BIOTECH

We are your pharma partner who covers all aspects of your project

Along the entire value chain

Discovery

Biomarker discovery

Structural Variants

Pre-clinical development

Variants

Clinical trials

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For all drug classes:

  • Patient screening regarding genetic conditions (exome/panel sequencing/ HWGS, microarray analysis)
  • Pharmacogenomics solutions (qPCR and microarraya)
  • Molecular monitoring of drug effect on gene expression levels (RNAseq and qPCR).

For novel therapies:

  • Manufacturing of templates (synthetic genes) and primers for mRNA production
    QC for mRNA templates, engineered cells in cell therapy (on-/off-target check), vectors and inserts

Coming soon: Synthesis of siRNAs, ASOs and other RNA therapeutics.

Commercial phase

Commercial phase

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Coming soon:
Manufacturing of templates (synthetic genes) and primers for mRNA production. Synthesis of siRNAs, ASOs and other RNA therapeutics.

QC for mRNA templates, treated cells in cell therapy (on-/off-target check), vectors and inserts.

Discovery

Biomarker discovery

Structural Variants

Pre-clinical development

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Manufacturing of small batches of therapeutic oligos or templates for mRNA production and toxicogenomic analysis.
Variants

Clinical trials

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For all drug classes:

  • Patient screening regarding genetic conditions (exome/panel sequencing/ HWGS, microarray analysis)
  • Pharmacogenomics solutions (qPCR and microarraya)
  • Molecular monitoring of drug effect on gene expression levels (RNAseq and qPCR).

For novel therapies:

  • Manufacturing of templates (synthetic genes) and primers for mRNA production
    QC for mRNA templates, engineered cells in cell therapy (on-/off-target check), vectors and inserts

Coming soon: Synthesis of siRNAs, ASOs and other RNA therapeutics.

Commercial phase

Commercial phase

Read more

Coming soon:
Manufacturing of templates (synthetic genes) and primers for mRNA production. Synthesis of siRNAs, ASOs and other RNA therapeutics.

QC for mRNA templates, treated cells in cell therapy (on-/off-target check), vectors and inserts.

Covering the entire range of theɾapeutics classes

Small molecules

Small molecules

Antibodies and other protein therapeutics

RNA therapeutics

RNA therapeutics

Cell theɾapγ

Small molecules

Small molecules

Antibodies and other protein therapeutics

RNA therapeutics

RNA therapeutics

Cell theɾapγ

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Small molecules to impact gene expression levels in the field of pharmacogenomics and toxicogenomics.

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Genomics solutions for:

  • Reliable production of protein coding synthetic gene including sequence optimisation.
  • Sequence screening and confirmation of produced constructs from small to high throughput.
  • Antibody purificationa according to your requirements.

Read more

Manufacturing of synthetic gene templates and primers for mRNA production. Quality control for mRNA templates.

Coming soon: Synthesis of siRNAs, ASOs and other RNA therapeutics.

Read more

Pharmacogenomics solutions for:

  • Patient screening for individualised therapy
  • Quality control for engineered cells
    (confirmation of on-target effects and check for off-target effects)
  • Quality control for vectors and inserts

Providing pharmacogenomics solutions for „hot topics“

Biomarkers

Microbiome

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Microbiome and metagenome characterisation and monitoring by targeted 16S and ITS amplicon sequencing or full microbial genome sequencing.

Processing and sequencing of samples from various sources like stool or skin swabs.

Pharmacogenomics

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Analysis of genetic precondition for metabolising different active substances:

  • Anaylsis of individual pathways using Sanger sequencing or qPCR
  • Holistic screening using microarray
Biobanking

Toxicogenomics

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Analyse the effect of drugs on different cellular pathways and molecular mechanisms.

RNASeq and microarrays are ideal high-throughput toxicogenomics solutions to analyse changes in gene expression.

Microbiome

Read more

Microbiome and metagenome characterisation and monitoring by targeted 16S and ITS amplicon sequencing or full microbial genome sequencing.

Processing and sequencing of samples from various sources like stool or skin swabs.

Pharmacogenomics

Read more

Analysis of genetic precondition for metabolising different active substances:

  • Anaylsis of individual pathways using Sanger sequencing or qPCR
  • Holistic screening using microarray
Biobanking

Toxicogenomics

Read more

Analyse the effect of drugs on different cellular pathways and molecular mechanisms.

RNASeq and microarrays are ideal high-throughput toxicogenomics solutions to analyse changes in gene expression.

The one pharma provider with all the solutions for your project

Benefit from our large network of labs and technologies

Eurofins Genomics, as part of Eurofins Scientific, is a market leader in testing and laboratory services for genomics, discovery pharmacology and clinical studies.

We support from research to application:

Pharma   |   Diagnostics   |   Biotechnology

With our globally unrivalled lab network, we support standard and challenging research projects, as well as complex strategies for large interdisciplinary companies.

Full scalability

 

 

100 %

From one to thousands of samples.
Don’t be afraid to think big!

tackle your challenges

Our technologies

We provide everything you need:

You are in good company – we are approved by our prees

Eurofins Genomics is a trusted brand around the globe

Eurofins genomics is a trusted brand around the globe

We cooperate with almost all of the TOP 20 Big Pharma companies

We cooperate with renowned organisations ranging from small-, medium- and large-scale enterprises to academic institutions. We provide leading expertise and sequencing capabilities that are needed to address some of today’s most important scientific and technical challenges.

We are scientific partners with

We are cooperation partners with

We are scientific partners with

We are cooperation partners with

Our Logistic Solutions provide:

Simple and straightforward sample taking and shipment

SIMPLE SAMPLE TAKING
We send you kits with easy-to-follow instructions on how to take samples.

CONVENIENT SAMPLE SHIPMENT
Send back the kits directly or use our dropboxes for shipping.

Make use of our global network of logistics partners and send your samples safely.

Your dedicated pharmacogenomics Experts

Meet our Pharma Team

Pharma & Translational Genomics Markets, Europe

Matthias Pfeiffer

Matthias Pfeiffer

Avril Hamilton

Avril Hamilton

Beatrice Carlsson

Beatrice Carlsson

Josiane Chuisseu

Josiane Chuisseu

Jeppe Skytte

Jeppe Skytte

Anja Kellermann

Anja Kellermann

Quality is our second name

Work with fully certified pharmacogenomics partner

ISO 17025 certified

ISO 17025

Guaranteed confidentiality and integrity of testing data.


Testing results are recognised by authorities and customs, etc. for the release of pharmaceuticals and food and feed, in the case of legal implications.

ISO 13485 certified

ISO 13485

Full documentation and traceability of production processes.


Compliance with regulatory requirements in regard to EU, US and other national directives about medical devices, in vitro Diagnostics or medicinal products.


Quality management system is in line with the FDA QSR standards.

GCLP

Guaranteed confidentiality and integrity of clinical trial data.


Full protection of patient rights, safety and well-being.


Full compliance with GCLP regulatory requirements.


Acceptance of clinical study data by regulatory authorities in EU, US and worldwide.

ISA GLP certified

GLP

Full traceability of GLP study data.


GLP compliant archiving of study data and records.


Full compliance with GLP regulatory requirements (OECD, EMA, US-FDA, US-EPA).


Acceptance of non-clinical safety study data by regulatory authorities in EU, US and worldwide.

Genomics services for pharma applications

Pharma FAQs

Find the answers to frequently asked questions.

Q: Who will be my person of contact?

Your person of contact is Natalie Smith, Senior Pharma & Translational Genomics Manager. Natalie has an extensive pharmacogenomics expertise and over 18 years of experience in managing technical projects with large international scientific companies specialising in pharmacogenomics, bioinformatics, pharmaceutical drug release and genomics technologies.

Speak to our expert

Q: What genomics solutions and capacities are available?

We provide a broad range of genomics solutions to support your research and project:

  • Next-generation sequencing
  • Microarrays
  • qPCR / dPCR
  • Sanger sequencing
  • Oligo synthesis
  • Gene synthesis
  • DNA and RNA extractions

Our highly flexible and large NGS and Sanger sequencing capacities allow us to process any kind of sample type (GLP and non-GLP compliant) and sample sizes ranging from one to thousands of samples. NGS is performed on Illumina and Oxford Nanopore platforms.

For our microarray-based services, we built a dedicated facility in Galten, Denmark, where we utilise Illumina and Thermo Fisher microarray platforms. Our large microarray capacities enable us to support population genetics studies with genotyping data for thousands of samples for instance.

Our high-throughput qPCR and dPCR services are performed in 96 or 384 formats on Roche LightCycler and Fluidigm BioMark HD and EP1 systems.

Our oligo and gene synthesis capacities can cover projects of any size, from small to large scale. Our ISO 13485 certified oligo synthesis can be customised as required by customers. We produce oligos in tubes and plates at different concentrations, formats (dry or in solution), pooling, TATs, and even print stickers on plates among others.

The gene synthesis at Eurofins Genomics is done on state-of-the-art synthesiser and propriety machines. Our lean-optimised processes guarantee optimal gene synthesis including a wide range of modifications according to the customer requirements. Our gene synthesis also includes codon usage adaptation for optimal expression in the organism of interest.

Our extensive DNA and RNA extraction capabilities allow for the processing of virtually all starting materials and sample sizes; the most common sample types are animal tissue, cells and cultured cells, blood, bacterial cell pellets, FFPE and plant tissue. We apply automated extraction pipelines using column- or bead-based methods; manual DNA and RNA extraction is available upon request. Our DNA and RNA extraction services are ISO17025 certified.

Q: How long will it take to receive my results?

The turnaround time (TAT), which presents the time from sample receipt in our lab to the delivery of sequencing result, depends on the genomics solution and sample number. Our mission is to provide the fastest TAT possible and set new industry standards for TATs while further improving quality. This is accomplished by:

  • the utilisation of the most reliable, proven and market-leading technologies and platforms,
  • high sequencing and production capacities,
  • optimisation and lean management of our highly automated lab processes,
  • years of experience and long-standing in-depth expertise.
Genomics solutions TAT (starting from)
Exome sequencing 9 business days
Microarrays 5 business days
qPCR / dPCR 1 business day
Sanger sequencing Overnight
Oligo synthesis 1 business day
Gene synthesis 4 business days
DNA / RNA extractions 5 business days

Q: What solutions does Eurofins Genomics offer for genotyping and gene expression analysis?

We offer microarrays, NGS, Sanger sequencing and qPCR for genotyping and gene expression analyses.

Microarrays are often utilised for gene expression analyse and genotyping of organisms. Our flexible microarray solutions allow for the coverage of the entire transcriptome or only specific genes of interest.

Gene expression analyses and genotyping is also done with NGS. Here, genome, exome and transcriptome sequencing are used to gain unbiased data.

Sanger sequencing is also utilised for genotyping and the detection of specific mutations. However, it is rather used in the later stages of the biomarker validation process for instance.

Similarly, qPCR assays are used for the targeted analysis of the expression of specific genes and gene mutation in an organism. dPCR with mutation-specific probes can also be used for genotyping and gene expression analysis. Compared to qPCR, dPCR enables absolute quantification instead of relative quantification.

The choice of analysis technique highly depends on the specific requirements of your research and project. All techniques have advantages and disadvantages. Contact our genomics expert for a free consultation about assay design and validation.

Q: Can I get demo data analysis reports for the Eurofins Genomics NGS solutions?

You can view and download demo data analysis reports for:

Q: What are the accepted sample types?

NGS

Suitable sample types for resequencing:

  • Purified and RNA-free genomic DNA (gDNA)
  • Purified DNA from FFPE

Suitable sample types for exome sequencing:

  • Purified and RNA-free gDNA
  • Purified DNA from FFPE

Suitable sample types for RNA sequencing:

  • Isolated total RNA from fresh tissue
  • Isolated total RNA from FFPE samples

Suitable sample types for metagenome analysis:

  • Clinical research samples of human origin (e.g. swaps, faeces, lavage)
  • Upon request: food samples, environmental samples

Suitable sample types for microbiome analysis:

  • Purified and RNA-free DNA
  • PCR amplicons

Microarrays

Suitable sample types:

  • Cell lysates
  • Purified and RNA-free DNA

qPCR / dPCR

Suitable sample types:

  • Complementary DNA (cDNA) for qPCR
  • Purified RNA or DNA for dPCR

Sanger sequencing

All types of sample material with biosafety level S1 and S2 (e.g. genomic DNA, Plasmid DNA, PCR amplicons, tissue, cell cultures, viral samples)

DNA and RNA extraction

We also provide DNA and RNA extraction from FFPE and tissue samples, whole blood, plasma and serum, cell cultures. For detailed information about our extraction capabilities, contact our genomics expert.

Q: Does Eurofins Genomics provide packaging and shipping labels for sample shipment?

We provide eco-friendly packaging for sample shipment. The packaging is made of 100% recycled paper and certified with “Blue Angel”.

Use our free paper bags or Böxles (sample boxes) for the safe shipment of your samples and primers in tubes and/or plates for Sanger sequencing.

When sending your samples to the Eurofins Genomics lab in Ebersberg, Germany, you could use our padded C5 sized envelopes for safe shipment. The envelopes come with pre-printed delivery address labels.

Alternatively, use conventional shipping kits from UPS and DHL, and envelopes.

We also provide free address labels for the sample shipment in your own sample bags to our labs in Ebersberg and Cologne, Germany.

Use the free sample pick-up via our DropBoxes. Just drop you sequencing samples (and primers) in the DropBox at your facility, and they will be collected free of charge. We have an extensive network with hundreds of DropBoxes across Europe. Find the closest DropBox (including pick-up time) in your Eurofins Genomics account. If there is no DropBox close you, send us a request to install a DropBox.

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